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Losartan Potassium & Hydrochlorothiazide 50mg Tablets is a combination medication used to treat hypertension (high blood pressure). It contains two active ingredients: Losartan Potassium, which belongs to a group of medications called angiotensin II receptor blockers (ARBs), and Hydrochlorothiazide, which is a diuretic (water pill). Losartan Potassium works by blocking the action of a hormone called angiotensin II, which causes blood vessels to narrow and the blood pressure to increase. Hydrochlorothiazide works by helping the kidneys eliminate excess salt and water from the body, which also helps to lower blood pressure. This medication is usually taken once daily, with or without food. The dosage may vary depending on your medical condition and response to treatment. It's important to take this medication exactly as prescribed and to continue taking it even if you feel well.